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IDWeek 2014: Behavioral and Financial Incentives May Improve HIV Treatment Outcomes

While making medications free can remove barriers to access for individuals who cannot pay for treatment, data suggest that for most people accessing care in industrialized countries, "making medications available for free or low cost will not solve problems with medication non-adherence," according to a presentation by Kevin Volpp from the University of Pennsylvania last week at IDWeek 2014 in Philadelphia.

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IDWeek 2014: HIV Attachment Inhibitor BMS-663068 Works Well Across Patient Subgroups

An experimental attachment inhibitor that binds to the surface of the HIV envelope and prevents it from attaching to and entering CD4 T-cells demonstrated good virological response rates and tolerability regardless of age, sex, or race/ethnicity, according to research presented at IDWeek 2014, now underway in Philadelphia.

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USCA 2014: U.S. Conference on AIDS Underway in San Diego

The 18th annual U.S. Conference on AIDS, sponsored by the National Minority AIDS Council, is taking place this week in San Diego. While other conferences focus on new data about antiretroviral therapy and biomedical prevention, USCA emphasizes the social, economic, and cultural aspects of HIV/AIDS.

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IDWeek 2014: HIV Care Cascade at Kaiser Permanente Varies by Sex and Age

Though there has been improving performance of healthcare delivery at each point of the HIV care cascade, from linkage to care through viral suppression, "success varies significantly by age and gender, even in an integrated care system with equal access to care,” Michael Horberg of the Mid-Atlantic Permanente Research Institute reported yesterday at IDWeek 2014 in Philadelphia.

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Monkey Transplant Study Rules Out Possible HIV Cure Mechanism

Macaque monkeys that received transplants of their own stem cells after undergoing intensive radiation that killed off their existing SHIV-infected immune cells experienced viral rebound soon after stopping antiretroviral drugs, indicating that pre-transplant "conditioning" was not solely responsible for the only known case of a person cured of HIV.

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Second Potentially Cured Baby Has HIV Relapse Soon After Stopping Treatment

An Italian child who started antiretroviral treatment soon after birth and had undetectable plasma viral load, no apparent HIV DNA, and tested HIV antibody negative nevertheless experienced viral rebound shortly after a treatment interruption, once again disappointing hopes for a cure, researchers reported in the October 4 edition of The Lancet.

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FDA Approves Elvitegravir and Cobicistat Booster as Stand-alone Drugs

The U.S. Food and Drug Administration (FDA) this week approved Gilead Sciences next-generation HIV integrase inhibitor elvitegravir (brand name Vitekta) and pharmacoenhancer cobicistat (Tybost) as stand-alone agents to be used in combination antiretroviral therapy. The 2 drugs were already available as part of the Stribild single-tablet regimen.

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