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ICAAC 2013: Depression Linked to Detectable HIV in Cerebrospinal Fluid

People who experience episodes of major depressive disorder (MDD) are significantly more likely to have detectable HIV in their cerebral-spinal fluid (CSF), according to an analysis of the large CHARTER study presented as a late-breaker poster at the 53rd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2013) last week in Denver.

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Coverage of 2013 Interscience Conference on Antimicrobial Agents and Chemotherapy

HIVandHepatitis.com coverage of the 53nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Denver, September 9-13, 2013.

Highlights of this year's meeting include experimental antiretroviral drugs and treatment strategies, CD4 cell gene therapy, HIV/HCV coinfection, liver transplants for people with HIV, and other sexually transmitted infections.

Full listing by topic

HIVandHepatitis.com ICAAC 2013 conference section

9/13/13

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Neurocognitive Impairment Common Among Youth with HIV

Approximately two-thirds of HIV positive young adults showed evidence of HIV-associated neurocognitive disorders (HAND), including impaired memory and fine motor control, according to a report in the August 21, 2013, advance edition of the Journal of Adolescent Health.

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ICAAC 2013: Raltegravir Safest for HIV+ Patients on Cancer Chemotherapy

The integrase inhibitor raltegravir (Isentress) may be an optimal choice for many HIV positive people undergoing cancer chemotherapy, as it is highly effective and well-tolerated in this population, according to a poster presentation at the 53rd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2013) this week in Denver.

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Preventive Antibiotics for Tuberculosis Lower Risk of Death for People with HIV

Increased screening for tuberculosis (TB) and prophylactic treatment with isoniazid significantly reduced the incidence of active TB disease as well as mortality among patients treated at HIV clinics in Brazil, according to a study published in the August 14, 2013, advance edition of Lancet Infectious Diseases. This is the first evidence that a community-wide effort can prevent people coinfected with HIV and TB from developing active TB disease.

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Low CD4 Count at Start of HIV Treatment Linked to Greater Bone Loss

People who had low CD4 T-cell counts when they started antiretroviral therapy (ART) were significantly more likely to experience bone loss after ART initiation, especially if they also had high viral load, researchers reported in the August 13, 2013, advance edition of Clinical Infectious Diseases.

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Exercise Linked to Less Cognitive Impairment Among People with HIV

HIV positive people who recently engaged in physical exercise were about half as likely to show signs of neurocognitive impairment -- including impaired working memory and slower information processing -- as those who did not, according to a study published in the August 10, 2013, advance edition of the Journal of Neurovirology.

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Recent Studies Shed Light on Cancer Among People with HIV

Starting antiretroviral therapy (ART) with a low CD4 count raises the likelihood of certain cancers, but others increase with longer time on therapy, reflecting a rising risk associated with older age, according to a recently published study. Other new research revealed increases in malignancies related to viral infections and a higher risk of Kaposi sarcoma even after immune restoration.

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IAS 2013: People with HIV Who Use Statins May Have Lower Cancer Risk

HIV positive people who use statins to manage high cholesterol also may reduce their risk of developing non-AIDS-defining malignancies, according to study findings reported at the recent 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2013) in Kuala Lumpur.

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