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Exercise Linked to Less Cognitive Impairment Among People with HIV

HIV positive people who recently engaged in physical exercise were about half as likely to show signs of neurocognitive impairment -- including impaired working memory and slower information processing -- as those who did not, according to a study published in the August 10, 2013, advance edition of the Journal of Neurovirology.

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IAS 2013: People with HIV Who Use Statins May Have Lower Cancer Risk

HIV positive people who use statins to manage high cholesterol also may reduce their risk of developing non-AIDS-defining malignancies, according to study findings reported at the recent 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2013) in Kuala Lumpur.

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IAS 2013: Second-line HIV Therapy with NRTIs Linked to Bone Loss [VIDEO]

Bone loss occurs less often when people on failing antiretroviral therapy switch to a NRTI-sparing second-line regimen containing raltegravir, researchers reported last week at the 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2013) this week in Kuala Lumpur.

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IAS 2013: End-Stage Kidney Disease Is More Common Among People with HIV

HIV positive people in the U.S. and Canada are nearly 4 times as likely to develop end-stage renal disease than HIV negative people in the general population, largely driven by a very high rate among blacks, researchers reported last month at the 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2013) in Kuala Lumpur.

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Coverage of the 2013 International AIDS Society Conference

HIVandHepatitis.com coverage of the 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2013), June 30-July 3, in Kuala Lumpur, Malaysia.

Conference highlights include antiretroviral therapy strategies, treatment access, investigational agents for HIV and hepatitis C, management of HIV-related complications, biomedical HIV prevention, and HIV cure research.

Full listing by topic

HIVandHepatitis.com IAS 2013 conference section

7/6/13

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FDA Limits Use of Oral Antifungal Ketoconazole Due to Side Effects and Drug Interactions

The antifungal drug ketoconazole (brand name Nizoral), used to treat certain AIDS-related opportunistic infections, should no longer be used as first-line oral therapy for any infection due to its potential to cause liver toxicity and adrenal gland problems, and instead should be reserved for those who cannot take or do not respond to other treatments, according to the U.S. Food and Drug Administration. The warning does not apply to topical formulations.

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Bone Loss and Fracture Risk are 'Modest' among HIV+ People, Linked to Tenofovir, Smoking, and HCV

Continued bone loss among HIV positive men with osteopenia was modest overall, but about 25% of those taking tenofovir (Viread, also in 4 antiretroviral coformulations) experienced significant loss, according to a recent study. A related meta-analysis found that HIV infection is associated with a modest likelihood of new fractures, with smoking and hepatitis C virus (HCV) coinfection further increasing the risk.

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IAS 2013: Studies Look at Second-Line Bone Changes, Fractures, and HIV- and HCV-Related Bone Loss

People with HIV experience less bone loss if they switch to a NRTI-sparing second-line regimen containing raltegravir, researchers reported last week at the 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2013) this week in Kuala Lumpur. Other studies showed that HIV infection is associated with increased risk of hip fractures and shed light on different mechanisms of bone loss associated with HIV and hepatitis C.

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CROI 2013: Random Anal Biopsies Improve Detection of Pre-cancerous Lesions

Performing random anal biopsies increases the rate of diagnosis of high-grade squamous intraepithelial lesions (HSIL) during high-resolution anoscopy, researchers from Mt. Sinai School of Medicine in New York City reported at the recent 20th Conference on Retroviruses and Opportunistic Infections (CROI 2013).alt

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