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Working Group Releases Guidelines for Improved Care of HIV-associated Cognitive Impairment

All people with HIV should be screened for HIV-associated neurocognitive disorders soon after testing positive, and those with evidence of impairment should be monitored regularly, according to international consensus guidelines developed by the Mind Exchange Working Group published in the November 28, 2012, advance edition of Clinical Infectious Diseases. Beyond antiretroviral therapy (ART), however, there are limited options for managing neurocognitive problems.

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Coverage of 11th International Congress on Drug Therapy in HIV Infection

HIVandHepatitis.com coverage of the 11th International Congress on Drug Therapy in HIV Infection (HIV11), November 11-15, 2012, Glasgow, Scotland.

Conference highlights include experimental antiretroviral drugs, ART strategies, manging side effects, HIV-related non-AIDS conditions, treatment as prevention and PrEP, HIV/HCV coinfection, and the search for a cure for HIV.

Full listing by topic

HIVandHepatitis.com HIV11 conference section

11/17/12

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HIV Is a Major Contributor to Increase in Anal Cancer among U.S. Men

Increased incidence of anal cancer during the past 3 decades among men in the U.S. has been strongly influenced by the HIV epidemic, although a similar association was not observed for women, researchers reported in the October 5, 2012, advance edition of the Journal of the National Cancer Institute. alt

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Speed of Processing Training Can Improve Cognitive Function for People with HIV

Completing 10 hours of exercises designed to enhance mental processing speed led to improvements in cognitive functioning for middle-aged and older people with HIV and increased their ability to carry out daily tasks, researchers reported in the November 2012 Journal of the Association of Nurses in AIDS Care.  alt

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Efavirenz Metabolism May Damage Neurons, Contribute to Neurocognitive Problems

Metabolites produces during processing of the widely used NNRTI efavirenz (Sustiva, also in the Atripla combination pill) can reach high levels in the brain, which can be toxic to neurons and interfere with cell signaling, according to a report in the September 19, 2012, online edition of the Journal of Pharmacology and Experimental Therapeutics. alt

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CDC Recommends Pneumococcal Vaccine Combo for Immune Compromised People

Immunocompromised individuals, including people with HIV, should receive both the 13-valent pneumococcal conjugate vaccine Prevnar 13 and the 23-valent pneumococcal polysaccharide vaccine Pneumovax 23 to prevent pneumococcal pneumonia and invasive disease, according to the latest recommendations from the Centers for Disease Control and Prevention (CDC). alt

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Bacterial Meningitis Outbreak among HIV Positive Gay Men in New York

New York City's Department of Health and Mental Hygiene (DHMH) last week announced that it is investigating a cluster of cases of invasive meningococcal disease over the past 2 years involving 12 men who have sex with men, a majority with HIV, of whom 4 have died. alt

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Methadone Use Reduces Risk of HIV Infection among Injection Drug Users

Methadone maintenance therapy is associated with a lower risk of HIV infection among people who inject drugs, though this may be attributable in part to differing behavior among people who do and do not seek treatment for addiction, according to a report in the October 3, 2012, British Medical Journal. alt

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ICAAC 2012: Bone Loss Is Common in French HIV Cohort, Linked to Older Age and Lower Weight

As many as half of people with HIV may have some degree of bone loss -- and up to 20% may experience fractures -- but no other significant risk factors could be determined other than older age and low body mass index, researchers reported at the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) this month in San Francisco. alt

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