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CDC Recommends Pneumococcal Vaccine Combo for Immune Compromised People

Immunocompromised individuals, including people with HIV, should receive both the 13-valent pneumococcal conjugate vaccine Prevnar 13 and the 23-valent pneumococcal polysaccharide vaccine Pneumovax 23 to prevent pneumococcal pneumonia and invasive disease, according to the latest recommendations from the Centers for Disease Control and Prevention (CDC). alt

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Methadone Use Reduces Risk of HIV Infection among Injection Drug Users

Methadone maintenance therapy is associated with a lower risk of HIV infection among people who inject drugs, though this may be attributable in part to differing behavior among people who do and do not seek treatment for addiction, according to a report in the October 3, 2012, British Medical Journal. alt

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ICAAC 2012: Bone Loss Is Common in French HIV Cohort, Linked to Older Age and Lower Weight

As many as half of people with HIV may have some degree of bone loss -- and up to 20% may experience fractures -- but no other significant risk factors could be determined other than older age and low body mass index, researchers reported at the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) this month in San Francisco. alt

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HIV Is a Major Contributor to Increase in Anal Cancer among U.S. Men

Increased incidence of anal cancer during the past 3 decades among men in the U.S. has been strongly influenced by the HIV epidemic, although a similar association was not observed for women, researchers reported in the October 5, 2012, advance edition of the Journal of the National Cancer Institute. alt

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ICAAC 2012: Are Statins Beneficial for Patients with Candida Fungal Infections?

Use of statin drugs to manage elevated cholesterol in people at risk for cardiovascular disease may also reduce short-term mortality among people with Candida fungal infections, perhaps due to their immunomodulatory properties,according to a study presented at the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) this week in San Francisco.alt

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Efavirenz Metabolism May Damage Neurons, Contribute to Neurocognitive Problems

Metabolites produces during processing of the widely used NNRTI efavirenz (Sustiva, also in the Atripla combination pill) can reach high levels in the brain, which can be toxic to neurons and interfere with cell signaling, according to a report in the September 19, 2012, online edition of the Journal of Pharmacology and Experimental Therapeutics. alt

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ICAAC 2012: Progression of Anal Neoplasia is Common among Gay Men with HIV

Nearly 40% of HIV positive men with low-grade anal neoplasia may progress to high-grade neoplasia or anal cancer, according to a Spanish study presented at the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) this week in San Francisco. Younger age and shorter duration of HIV infection were risk factors for worsening disease.alt

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Bacterial Meningitis Outbreak among HIV Positive Gay Men in New York

New York City's Department of Health and Mental Hygiene (DHMH) last week announced that it is investigating a cluster of cases of invasive meningococcal disease over the past 2 years involving 12 men who have sex with men, a majority with HIV, of whom 4 have died. alt

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ICAAC 2012: Atazanavir Linked to Kidney Stones in People with HIV coverage of the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), San Francisco, September 9-12, 2012.

Topics highlighted this year include experimental antiretroviral drugs, complications related to HIV and its treatment, recent developments in hepatitis C therapy, cancer caused by HPV, influenza, tuberculosis, and STDs.

Full listing by topic ICAAC 2012 conference section