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Efavirenz Metabolism May Damage Neurons, Contribute to Neurocognitive Problems

Metabolites produces during processing of the widely used NNRTI efavirenz (Sustiva, also in the Atripla combination pill) can reach high levels in the brain, which can be toxic to neurons and interfere with cell signaling, according to a report in the September 19, 2012, online edition of the Journal of Pharmacology and Experimental Therapeutics. alt

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Bacterial Meningitis Outbreak among HIV Positive Gay Men in New York

New York City's Department of Health and Mental Hygiene (DHMH) last week announced that it is investigating a cluster of cases of invasive meningococcal disease over the past 2 years involving 12 men who have sex with men, a majority with HIV, of whom 4 have died. alt

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ICAAC 2012: Atazanavir Linked to Kidney Stones in People with HIV

HIVandHepatitis.com coverage of the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), San Francisco, September 9-12, 2012.

Topics highlighted this year include experimental antiretroviral drugs, complications related to HIV and its treatment, recent developments in hepatitis C therapy, cancer caused by HPV, influenza, tuberculosis, and STDs.

Full listing by topic

HIVandHepatitis.com ICAAC 2012 conference section

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ICAAC 2012: Bone Loss Is Common in French HIV Cohort, Linked to Older Age and Lower Weight

As many as half of people with HIV may have some degree of bone loss -- and up to 20% may experience fractures -- but no other significant risk factors could be determined other than older age and low body mass index, researchers reported at the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) this month in San Francisco. alt

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Coverage of Interscience Conference on Antimicrobial Agents and Chemotherapy

HIVandHepatitis.com coverage of the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy -- better known as ICAAC -- in San Francisco, September 9-12, 2012.

Topics highlighted this year include experimental antiretroviral drugs, complications related to HIV and its treatment, recent developments in hepatitis C therapy, and cancer caused by HPV, along with a gamut of other infectious diseases including influenza, tuberculosis, and STDs.

Full listing by topic

HIVandHepatitis.com ICAAC 2012 conference section

9/11/12

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ICAAC 2012: Are Statins Beneficial for Patients with Candida Fungal Infections?

Use of statin drugs to manage elevated cholesterol in people at risk for cardiovascular disease may also reduce short-term mortality among people with Candida fungal infections, perhaps due to their immunomodulatory properties,according to a study presented at the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) this week in San Francisco.alt

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ICAAC 2012: HIV+ People Have Heart Attacks Younger, Receive Later Care, Die More Often

People with HIV had heart attacks at a younger age than HIV negative individuals and were about 50% more likely to die after an acute myocardial infarction, according to a study presented this week at the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) in San Francisco. A related analysis found that HIV positive people received coronary catheterization at a later stage, after they had more advanced heart damage.alt

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ICAAC 2012: Progression of Anal Neoplasia is Common among Gay Men with HIV

Nearly 40% of HIV positive men with low-grade anal neoplasia may progress to high-grade neoplasia or anal cancer, according to a Spanish study presented at the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) this week in San Francisco. Younger age and shorter duration of HIV infection were risk factors for worsening disease.alt

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ICAAC Meeting Underway in San Francisco -- HIV, HCV, HPV, Flu, and More

The 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy -- better known as ICAAC -- opened Sunday, September 9, at San Francisco's Moscone Center.alt

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