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AIDS 2016: Early HIV Treatment -- Mothers Say They Need Time to Think

Findings from the first randomized controlled trial to date evaluating postpartum antiretroviral therapy (ART) for women with high CD4 cell counts (over 400 cells/mm3) highlight a critical need to increase treatment acceptance in this population, according to research presented at the 21st International AIDS Conference (AIDS 2016) last week in Durban.

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AIDS 2016: HIV Stigma Persists in the Undetectable Era

In an era of widespread HIV treatment and undetectable viral load, stigma remains a persistent feature in the lives of almost half of people living with diagnosed HIV in the U.K., according to findings from The People Living with HIV Stigma Survey UK 2015, reported at the 21st International AIDS Conference (AIDS 2016) last week in Durban. Nonetheless the majority of people with HIV score highly on measures of psychological resilience, enabling them to cope better with stigma.

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AIDS 2016: Study Looks at Comprehensive HIV Treatment and Prevention Services for Sex Workers

A randomized trial of female sex workers in Zimbabwe, offering enhanced access to HIV treatment and pre-exposure prophylaxis (PrEP), has failed to show that the extra services helped reduce the proportion with detectable viral load, Frances Cowan reported at the 21st International AIDS Conference (AIDS 2016) last week in Durban. However, it appears that the comprehensive set of sex worker-friendly services offered in the control arm may have already been enough to substantially improve the health of participants.

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AIDS 2016: Once-Daily Raltegravir Works as Well as Twice-Daily For Initial HIV Treatment

A new formulation of the integrase inhibitor raltegravir (Isentress) taken once daily suppressed HIV viral load as well as the older formulation taken twice a day in people being treated for the first time, according to findings from the ONCEMRK study presented in a late-breaker session at the 21st International AIDS Conference (AIDS 2016) last week in Durban.

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AIDS 2016: Large Test-and-Treat Study Fails to Show Impact on New HIV Infections

The first major research study of "test and treat" as a public health intervention to report its final results -- ANRS 12249 -- has found that the strategy failed to reduce new HIV infections in the African communities where it was provided, according to a report at the 21st International AIDS Conference (AIDS 2016) last week in Durban.

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AIDS 2016: Bone Loss Recovers After Stopping PrEP, Biannual Kidney Monitoring Enough for Most

Young adults taking Truvada for pre-exposure prophylaxis (PrEP) experienced a modest decrease in bone mineral density early on, but this stabilized after a year and those who stopped taking it began to see a reversal of the decline, researchers reported last week at the 21st International AIDS Conference (AIDS 2016) in Durban. Another study found that clinically relevant declines in kidney function among Truvada PrEP users are rare and monitoring every 6 months is adequate for most people.

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AIDS 2016: Progress Towards 90-90-90 Targets in Southern Africa -- Find the Men!

Studies of treatment cascade performance in South Africa and Namibia show large variations between districts and highlight the need for up-to-date information on performance to guide programming, advocacy, and funding, according to presentations at the 21st International AIDS Conference (AIDS 2016) last week in Durban. In particular, the studies emphasized the low rates of HIV diagnosis among men in the region, and low rates of viral suppression, especially among men.

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