Back HIV/AIDS

HIV / AIDS

U.S. On Course to End Its HIV Epidemic -- Eventually

If current trends continue, the U.S. may eventually end its HIV epidemic, a mathematical model recently published in AIDS and Behavior shows. In 2009, the average number of people each person with HIV would infect during their lifetime fell below 1, and has now declined to 0.75, the model shows. This means the number of people living with HIV will eventually start to shrink, as more aging HIV-positive people start to die than new people getting infected. For the moment, however, since mortality among people with HIV also continues to fall, the number of people living with the virus continues to grow slowly.

alt

Diagnosis of Early HIV Infections May Have Contributed to Fall in Incidence in San Diego

An HIV testing program targeting individuals with acute or early infection likely contributed to a decline in incident or new infections in San Diego after 2008, investigators report in the May 11 online edition of Clinical Infectious Diseases. The Early Test initiative involved negative HIV antibody tests being rescreened using nucleic acid testing (NAT) -- a technique capable of detecting new HIV infections within 7-10 days after exposure.

alt

High Prevalence of Geriatric Conditions Among HIV+ People Over Age 50 in San Francisco

Older HIV-positive people have a high prevalence of multiple age-related problems, investigators reported in the March 29 online edition of the Journal of Acquired Immune Deficiency Syndromes. The research involved people aged 50 years and older receiving outpatient care in San Francisco. Overall, 40% reported difficulties with daily activities, most reported loneliness, many had mild cognitive impairment, and 30% had only poor to fair quality of life.

alt

Model Suggests There Are Fewer People with HIV in U.S. and More on Treatment

A study comparing recorded diagnoses of HIV with subsequent records of viral load and CD4 T-cell tests suggests that the number of people living with HIV in the U.S. could have been overestimated by as much as 45% -- and the proportion who are on antiretroviral therapy (ART) with undetectable viral loads could have been underestimated by as much as 50%. There could be as few as 820,000 people with HIV in the U.S. compared with the normally accepted figure of 1.2 million -- and up to 55% of those could be on ART and virally suppressed, compared with the most commonly quoted figure of 30%.

alt

U.S. Government Updates Guidelines for HIV Post-Exposure Prophylaxis

The U.S. Centers for Disease Control and Prevention (CDC) and Department of Health and Human Services (DHHS) in April issued their latest guidelines for non-occupational post-exposure prophylaxis (PEP) for people potentially exposed to HIV through sex or shared injection equipment. The update includes new antiretrovirals approved since the last revision, with the preferred regimen now being raltegravir (Isentress) or dolutegravir (Tivicay) plus tenofovir/emtricitabine (the drugs in Truvada).

alt

BHIVA 2016: First Data on Uptake of HIV Self-Testing in the U.K.

Between April 2015 and February 2016, almost 28,000 people have paid £29.95 (about US$45) for a kit allowing them to test for HIV at home, according to a presentation at the recent British HIV Association (BHIVA) conference in Manchester. Marketing on Grindr has been important in driving sales, which have been concentrated in non-urban areas.

alt

Genvoya TAF Regimen Works Well with Improved Bone and Kidney Safety at 96 Weeks

The Genvoya single-tablet regimen containing tenofovir alafenamide (TAF) suppressed HIV as well as a similar coformulation containing the older tenofovir disoproxil fumarate (TDF), but demonstrated better bone and kidney tolerability after 2 years of treatment, according to a report in the May 1 edition of the Journal of Acquired Immune Deficiency Syndromes.

alt